OAS2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | OAS2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mousepredicted: bovine, horse, rabbit, dog |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: OAS2 Antibody detects endogenous levels of OAS2. Description: Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response (PubMed:10464285, PubMed:9880569). Activated by detection of double stranded RNA (dsRNA): polymerizes higher oligomers of 2'-5'-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNASEL) leading to its dimerization and subsequent activation (PubMed:10464285, PubMed:9880569, PubMed:11682059). Activation of RNASEL leads to degradation of cellular as well as viral RNA, resulting in the inhibition of protein synthesis, thus terminating viral replication (PubMed:10464285, PubMed:9880569). Can mediate the anti |
| Immunogen | Immunogen: A synthesized peptide derived from human OAS2. Tissue Specificity: By type I interferon (IFN) and viruses. |
| Other Names | [(2-5'')oligo(A) synthase 2; (2-5')oligo(A) synthetase 2; 2''-5''-oligoadenylate synthase 2; 2'-5'-oligoadenylate synthetase 2; 2'-5'-oligoadenylate synthetase 2, 69/71kDa; 2-5A synthase 2; 2-5A synthetase 2; 2-prime, 5-prime-oligoadenylate synthetase 2edit item name - 2-prime, 5-prime-oligoadenylate synthetase 2, 69-KD; 2-prime, 5-prime-oligoadenylate synthetase 2; MGC78578; OAS2; OAS2_HUMAN; p69; p69 OAS/p71 OAS; p69OAS/p71OAS] |
| Gene, Accession # | [OAS2], Gene ID: 4939, NCBI: P29728.3, UniProt: P29728 |
| Catalog # | MBS9611432 |
| Price | $240, $280 |
| Order / More Info | OAS2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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