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Antigenic Specificity | RBSN |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | biotin conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rab4/Rab5 effector protein acting in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Required for endosome fusion either homotypically or with clathrin coated vesicles. Plays a role in the lysosomal trafficking of CTSD/cathepsin D from the Golgi to lysosomes. Also promotes the recycling of transferrin directly from early endosomes to the plasma membrane. Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate (PtdInsP3) (PubMed:11062261, PubMed:11788822, PubMed:15020713). Plays a role in the recycling of transferrin receptor to the plasma membrane (PubMed:22308388). |
Immunogen | Immunogen: Recombinant human Rabenosyn-5 protein |
Other Names | [Rabenosyn-51; 110 kDa protein; FYVE finger-containing Rab5 effector protein rabenosyn-5; RAB effector RBSN; RBSN] |
Gene, Accession # | [RBSN], Gene ID: 64145, NCBI: NP_001289307.1, UniProt: Q9H1K0 |
Catalog # | MBS7000137 |
Price | $160, $235 |
Order / More Info | RBSN Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |