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Antigenic Specificity | GSK3 Beta (pTyr216) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse (expected from sequence), rat (expected from sequence) |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) Paraffin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti GSK3 Beta (pTyr216) antibody recognizes GSK3 beta when phosphorylated at tyrosine 216. GSK3 is a member of the CMGC family of kinases. GSK3 comprises two isoforms, alpha and beta, with 85% total homology and 98% homology between kinase domains. GSK3 beta is phosphorylated at tyrosine 216 via autophosphorylation, Fyn and PYK2. Phosphorylation of GSK3 beta at tyrosine 216 activates GSK3 alpha leading to phosphorylation of downstream targets such as the insulin receptor and glucose-6-phosphate. |
Immunogen | Immunogen: Phospho specific-peptide corresponding to residues surrounding tyrosine 216 of human GSK3 beta |
Other Names | [GSK3 Beta (pTyr216)], [GSK3B; GSK3B; GSK-3 beta] |
Gene, Accession # | [GSK3B], Gene ID: 2932, NCBI: P49841.2, UniProt: P49841 |
Catalog # | MBS225263 |
Price | $375 |
Order / More Info | GSK3 Beta (pTyr216) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |