Human MICA/MICB: Low Endotoxin Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human MICA/MICB: Low Endotoxin |
| Clone | [6D4] |
| Host Species | Mouse |
| Reactive Species | n/a |
| Isotype | IgG2a |
| Format | unconjugated |
| Size | 0.5 mg |
| Concentration | IgG concentration 1.0 mg/ml |
| Applications | Immunohistology Frozen, Flow cytometry (FC/FACS)*, Functional Assays (FN), Immunoprecipitation (IP) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Mouse anti Human MICA/Micb antibody, clone 6D4 recognizes nonclassical MHC class I chain A (MICA) and nonclassical MHC class I chain MICB (MICB). MICA and MICB are stress inducible antigens, which are closely related and appear functionally indistinguishable. MICA and MICB are ligands for NKG2D, an activating receptor on most natural killer (NK) cells, CD8 T cells and gamma delta T cells. MICA is principally expressed on intestinal epithelium, and several epithelial tumours. Expression may be induced to high surface levels by heat shock, oxidative stress, and virus infection. Clone 6D4 is reported to inhibit the cytotoxicity of NK cells stimulated by IFN alpha-treated dendritic cells (Jinushi et al. 2003). |
| Immunogen | n/a |
| Other Names | [MHC class I polypeptide-related sequence A isoform 1 (MICA*001); MHC class I polypeptide-related sequence A; MHC class I polypeptide-related sequence A; HLA class I antigen; MHC class I chain-related protein A; MICA; stress inducible class I homolog; MHC class I polypeptide-related sequence A], [MICA; MICA; MIC-A; PERB11.1; MIC-A] |
| Gene, Accession # | [MICA/MICB], Gene ID: 100507436, NCBI: NP_000238.1 |
| Catalog # | MBS211244 |
| Price | $675 |
| Order / More Info | Human MICA/MICB: Low Endotoxin Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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