Human CD107a/LAMP-1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human CD107a/LAMP-1 |
| Clone | [H4A3] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Flow Cytometry; Immunohistochemistry (Acetone Fixed/Frozen Sections) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Human CD107a/LAMP-1. CD107a, also known as lysosomal-associated membrane protein 1 (LAMP-1), is a heavily glycosylated, type I transmembrane protein that constitutes the major sialoglycoproteins on lysosomal membranes. It is a ligand for galaptin, an S-type lectin present in extracellular matrix, through its recognition of acetyllactosamine oligosaccharide chains, and is a ligand for E-selectin-mediated cell adhesion. CD107a is expressed by granulocytes, T cells, macrophages, dendritic cells, activated platelets, tonsillar epithelium and some tumor cell lines, including U937 and KG1a. It is also a widely expressed intracellular antigen. LAMP-1 may function in protecting the inner surface of the lysosomal membrane by forming a b |
| Immunogen | n/a |
| Other Names | n/a |
| Gene, Accession # | n/a |
| Catalog # | MBS674318 |
| Price | $170 |
| Order / More Info | Human CD107a/LAMP-1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Schlossman, S., L. Bloumsell, W. Gilks, J.M. Harlan, C. Kishimoto, J. Ritz, S. Shaw, R. Silverstein, T. Springer, T.F. Tedder, and R.F. Todd, eds. 1995. Leukocyte Typing V: White Cell Differentiation Antigens, Oxford University Press, Oxford.2. Barclay, A.N., M.H. Brown, S.K.A. Law, A.J. McKnight, M.G. Tomlinson, and P.A. van der Merwe, eds. 1997. The Leukocyte Antigens Facts Book, 2nd Edition, CD107a, 107b Section, Academic Press, New York, p. 389.3. Sawada, R., K.A. Jardine, and M. Fukuda. 1993. J. Biol. Chem. 268:9014.4. Febbraio, M., and R.L. Silverstein. 1990. J. Biol. Chem. 265:18531.5. Chen, J.W., Y. Cha, K.U. Yuksel, R.W. Gracy, and J.T. August. 1988. J. Biol. Chem. 263:8754.6. Sawada, R., J.B. Lowe, and M. Fukuda. 1993. J. Biol. Chem. 268:12675.7. Sawada, R., S. Tsuboi, and M. Fukuda. 1994. J. Biol. Chem. 269:1425. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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