KDM1A Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityKDM1A
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatantigen affinity purified
Size0.06 mL, 0.12 mL, 0.2 mL
Concentration1mg/mL
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), CHIP
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DescriptionLysine-specific demethylase 1 (LSD1; also known as AOF2 and BHC110) is a nuclear amine oxidase homolog that acts as a histone demethylase and transcription cofactor (1). Gene activation and repression is specifically regulated by the methylation state of distinct histone protein lysine residues. For example, methylation of histone H3 at Lys4 facilitates transcriptional activation by coordinating the recruitment of BPTF, a component of the NURF chromatin remodeling complex, and WDR5, a component of multiple histone methyltransferase complexes (2, 3). In contrast, methylation of histone H3 at Lys9 facilitates transcriptional repression by recruiting HP1 (4, 5). LSD1 is a component of the CoREST transcriptional co-repressor complex that also c
ImmunogenImmunogen: Recombinant protein of human KDM1A Observed Molecular Weight: 95kDa
Other Names[KDM1; AOF2; BHC110; KIAA0601; LSD1; KDM1A]
Gene, Accession #[KDM1A], NCBI: AIC62107.1
Catalog #MBS2528711
Price$150, $225, $360
Order / More InfoKDM1A Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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