DC-SIGN, Human Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityDC-SIGN, Human
CloneDCN47.5
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), FS
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DescriptionProduct Description: The monoclonal antibody DCN47.5 reacts with the C-type lectin, DC-SIGN (CD209), exclusively expressed on human dendritic cells (DC). DC are specialized antigen presenting cells and bridge the innate and the adaptive immune system. They provide high levels of costimulation necessary for activation of both na ve and antigen-experienced T-cells. Immature DC are capable to migrate to inflammatory sites, capture antigen and process it internally to form MHC-peptide complexes. Following antigen uptake, DC undergo maturation and migrate to lymphoid organs where they can present MHC-peptide complexes to resting T-cells and drive T-cell proliferation. During differentiation and maturation of DC, several phenotypic surface marker
Immunogenn/a
Other Names[DC-SIGN; CD209 antigen; CD209 antigen; HIV gpl20-binding protein; C-type lectin domain family 4 member L; C-type lectin domain family 4, member L; dendritic cell-specific ICAM-3-grabbing non-integrin 1; dendritic cell-specific intracellular adhesion molecules (ICAM)-3 grabbing non-integrin; CD209 molecule; C-type lectin domain family 4 member L; Dendritic cell-specific ICAM-3-grabbing non-integrin 1; DC-SIGN; DC-SIGN1; CD_antigen: CD209], [CD209; CD209; CDSIGN; CLEC4L; DC-SIGN; DC-SIGN1; CLEC4L; DC-SIGN; DC-SIGN1]
Gene, Accession #[DC-SIGN], Gene ID: 30835, NCBI: AAK20997.1
Catalog #MBS584034
Price$610
Order / More InfoDC-SIGN, Human Antibody from MYBIOSOURCE INC.
Product Specific ReferencesWhelan, K et al; The HIV protease inhibitor Indinavir reduces immature dendritic cell transendothelial migration. Eur J Immunol 2003, 33: 2520
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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