SCF Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySCF
Clonepolyclonal
Host Speciesn/a
Reactive Specieshuman
Isotypen/a
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThe antibody detects endogenous level of total SCF protein. Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG/SCF and KIT promote activation of STAT family members STAT1, STAT3 and STAT5. KITLG/SCF and KIT promo
ImmunogenImmunogen: Peptide sequence around aa.265~269(E-K-E-R-E) derived from Human SCF.
Other Names[SF; MGF; FPH2; KL-1; Kitl]
Gene, Accession #[SCF], Gene ID: 4254, NCBI: NP_000890.1, UniProt: P21583
Catalog #MBS8511718
Price$290
Order / More InfoSCF Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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