B7-H3/CD276 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityB7-H3/CD276
Clone[6A1]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatascites
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS), ELISA (EIA)
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DescriptionCostimulatory B7 molecules (e.g., B7-1, or CD80; MIM 112203) signal through CD28 (MIM 186760) family molecules such as CD28, CTLA4 (MIM 123890), and ICOS (MIM 604558). May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4
ImmunogenImmunogen: Purified recombinant fragment of human CD276 expressed in E. Coli.
Other Names[B7-H3 protein; CD276 antigen; CD276 antigen; CD276 molecule; 4Ig-B7-H3; B7 homolog 3; B7-H3; Costimulatory molecule]
Gene, Accession #[CD276], Gene ID: 80381, NCBI: CAE47548.1, UniProt: Q5ZPR3
Catalog #MBS8538681
Price$280
Order / More InfoB7-H3/CD276 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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