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Antigenic Specificity | HIPK1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Serine/threonine-protein kinase involved in transcription regulation and TNF-mediated cellular apoptosis. Plays a role as a corepressor for homeodomain transcription factors. Phosphorylates DAXX and MYB. Phosphorylates DAXX in response to stress, and mediates its translocation from the nucleus to the cytoplasm. Inactivates MYB transcription factor activity by phosphorylation. Prevents MAP3K5-JNK activation in the absence of TNF. TNF triggers its translocation to the cytoplasm in response to stress stimuli, thus activating nuclear MAP3K5-JNK by derepression and promoting apoptosis. May be involved in anti-oxidative stress responses. Involved in the regulation of eye size, lens formation and retinal lamination during late embryogenesis. Promo |
Immunogen | Immunogen: Recombinant Human Homeodomain-interacting protein kinase 1 protein (1007-1151AA) |
Other Names | [Homeodomain-interacting protein kinase 1; Nuclear body-associated kinase 2; HIPK1; KIAA0630; MYAK; NBAK2] |
Gene, Accession # | [HIPK1], Gene ID: 204851, NCBI: NP_689909.2, UniProt: Q86Z02 |
Catalog # | MBS7107403 |
Price | $160, $235 |
Order / More Info | HIPK1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |