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Antigenic Specificity | Human SIGLEC-10 |
Clone | [5G6] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 |
Format | fluorescein (FITC) conjugate |
Size | 0.1 mg |
Concentration | IgG concentration 0.1 mg/ml |
Applications | Flow cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Clone 5G6 specifically recognises human Siglec-10 (Sialic acid-binding Ig-like lectin 10), a putative adhesion molecule and member of the Ig superfamily, expressed by monocytes, B cells, eosinophils, and at a higher level by a subpopulation of CD16+CD56- natural killer (NK) cells. . . Structurally, Siglec-10 is most similar to the CD33-related group of Siglecs, and preferentially binds to glycoconjugates containing alpha-2,3- or alpha-2,6-linked sialic acid. Studies have shown that Siglec-10 acts as a substrate for VAP-1 (Vascular adhesion protein-1), a glycoprotein expressed on endothelium during inflammation, which is involved in primary amine oxidation and leucocyte trafficking, see Kive, E. et al. for details. This intera |
Immunogen | Immunogen: Recombinant human Siglec-10, fused with the Fc region of human IgG Buffer Solution: Phosphate buffered saline Target Species: Human |
Other Names | [sialic acid-binding Ig-like lectin 10 isoform 2; Sialic acid-binding Ig-like lectin 10; sialic acid-binding Ig-like lectin 10; sialic acid binding Ig-like lectin 10 Ig-like lectin 7; siglec-like gene 2; siglec-like protein 2; sialic acid binding Ig-like lectin 10; Siglec-like protein 2], [SIGLEC10; SIGLEC10; SLG2; PRO940; SIGLEC-10; SLG2; Siglec-10] |
Gene, Accession # | [SIGLEC-10], Gene ID: 89790, NCBI: NP_001164627.1, UniProt: Q96LC7 |
Catalog # | MBS224376 |
Price | $370 |
Order / More Info | Human SIGLEC-10 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |