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Antigenic Specificity | TACI |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Members in the TNF superfamily regulate immune responses and induce apoptosis. Two novel members in the TNF family were recently identified and designated BAFF/BLyS/TALL-1/THANK/zTNF4 and April/TALL-2, respectively. BAFF was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. April regulates immunological and non-immunological cell growth. Three receptors, BCMA, TACI, and BAFF-R, for BAFF and April were recently identified. TACI, like BCMA, binds BAFF and April. TACI and its ligands regulate humoral immune responses, activate NF-kB and c-jun N-terminal kinase, and are involved in B cell associated autoimmune diseases. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a synthetic peptide mapping at the amino terminus of human TACI. |
Other Names | [tumor necrosis factor receptor superfamily member 13B; Tumor necrosis factor receptor superfamily member 13B; tumor necrosis factor receptor superfamily member 13B; tumor necrosis factor receptor superfamily, member 13B; Transmembrane activator and CAML interactor; CD_antigen: CD267] |
Gene, Accession # | [TACI], Gene ID: 23495, NCBI: NP_036584 |
Catalog # | MBS9411079 |
Price | $320 |
Order / More Info | TACI Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |