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Antigenic Specificity | Nestin (S1409), 1389-1416 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.32 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Nestin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1389-1416 amino acids from human Nestin. Nestin is a class VI intermediate filament protein expressed predominantly in stem cells of the neural tube but absent from virtually all differentiated CNS cells. In the CNS, nestin is downregulated upon differentiation and replaced by neurofilaments. Transient expression of nestin has been postulated as a key step committing cells to the neural differentiation pathway. Nestin expression has also been observed in pancreatic hematopoietic stem cell populations. |
Immunogen | n/a |
Other Names | [Nestin; NES] |
Gene, Accession # | [NES], Gene ID: 10763, NCBI: NP_006608.1, UniProt: P48681 |
Catalog # | MBS9203158 |
Price | $165, $370 |
Order / More Info | Nestin (S1409), 1389-1416 Antibody from MYBIOSOURCE INC. |
Product Specific References | References for protein 1.Yaworsky, P.J., et al., Dev. Biol. 205(2):309-321 (1999). 2.Dahlstrand, J., et al., J. Cell. Sci. 103 (Pt 2), 589-597 (1992). References for SY5Y (SH-SY5Y; ATCC#CRL-2266): 1. Ross RA, et al. Coordinate morphological and biochemical interconversion of human neuroblastoma cells. J. Natl. Cancer Inst. 71: 741-749, 1983. [PubMed: 6137586]; 2. Biedler JL, et al. Multiple neurotransmitter synthesis by human neuroblastoma cell lines and clones. Cancer Res. 38: 3751-3757, 1978. [PubMed: 29704]. |