Matrilysin (MMP7) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Matrilysin (MMP7) |
| Clone | [3H34] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2b |
| Format | Protein A purified |
| Size | 0.1 mg |
| Concentration | ~1 mg/mL (after reconstitution) |
| Applications | Suitable for use in ELISA (EIA) and Western Blot (WB). Other applications not tested. |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Recognizes both latent and active forms of MMP7. Matrix metalloproteinase-7 (MMP-7) also known as matrilysin and PUMP (EC 3.4.24.23) cleaves a number of substrates including collagen types IV and X, elastin, fibronectin, gelatin, laminin and proteoglycans. MMP-7 is closely related to the stromelysin family members but is encoded by a different gene. MMP-7 is the smallest of all the MMPs consisting of a pro-peptide domain and a catalytic domain. It lacks the hemopexin-like domain common to other members of the MMPs. MMP-7 is secreted as a 28kD proenzyme and can be activated in vitro by organomercurials and trypsin and in vivo by MMP-3 to a 18kD active MMP-7 enzyme. Once activated, MMP-7 can activate pro-MMP-1 and pro-MMP-9 but not pro-MMP-2. |
| Immunogen | Immunogen: Recombinant protein corresponding to Human MMP7 has been expressed in E. Coli. Grade: Affinity purified |
| Other Names | [Matrilysin (MMP7)], [MMP7; MMP7; MMP-7; MPSL1; PUMP-1; MPSL1; PUMP1] |
| Gene, Accession # | Gene ID: 4316, NCBI: NP_002414.1, UniProt: P09237 |
| Catalog # | MBS602860 |
| Price | $745 |
| Order / More Info | Matrilysin (MMP7) Antibody from MYBIOSOURCE INC. |
| Product Specific References | • 1. Harder et al (1997) Nature 387, 861; Ganz T (1999) Science 286, 420; Yang D et al (1999) Science 286, 525; Wilson CL et al (1999) Science 286, 113-117; Cottman DW et al (1993) Intl J. Oncol. 2, 861-872; Wossner JF et al (1995) Methods Enzymol. 248, 485-495; Imai K et al (1995) J. Biol. Chem. 269, 2032-2040; Brunner KL et al (1995) Proc. Natl. Acad. Sci. 92, 7362-7366 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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