Phospho-MSK2 (Thr687) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-MSK2 (Thr687)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, ratpredicted: porcine, zebrafish, bovine, horse, dog, Xenopus
Isotypen/a
Formatpeptide affinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Peptide ELISA (EIA)
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DescriptionSpecificity: Phospho-MSK2 (Thr687) Antibody detects endogenous levels of MSK2 only when phosphorylated at Thr687. Description: Serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factor RELA, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes. Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin. Plays an essential role in the control of RELA transcriptional activity in response to TNF. Phosphorylates 'Ser-10' of histone H3 in response to mitogenics,
ImmunogenImmunogen: A synthesized peptide derived from human MSK2 around the phosphorylation site of Thr687.
Other Names[90 kDa ribosomal protein S6 kinase 4; EC 2.7.11.1; KS6A4_HUMAN; Mitogen and stress activated protein kinase 2; Nuclear mitogen and stress activated protein kinase 2; Nuclear mitogen- and stress-activated protein kinase 2; Ribosomal protein kinase B; Ribosomal protein S6 kinase 90kD polypeptide 4; Ribosomal protein S6 kinase 90kDa polypeptide 4; Ribosomal protein S6 kinase alpha 4; Ribosomal protein S6 kinase alpha-4; RPS6KA4; RSKB; S6K-alpha-4]
Gene, Accession #[MSK2], Gene ID: 8986, NCBI: NP_001006945.1, UniProt: O75676
Catalog #MBS9610518
Price$225, $280, $340
Order / More InfoPhospho-MSK2 (Thr687) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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