Human CEACAM1,3,4,5,6 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman CEACAM1,3,4,5,6
Clone[D14HD11]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
FormatProtein G purified
Size0.1 mg
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), CELISA, ELISA (EIA), Western Blot (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistology on cryosections
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DescriptionSpecificity: anti-human CEACAM1,3,4,5,6 (CD66a,c,d,e,CGM7). Background: CEA-related cell adhesion molecules (CEACAM) belong to the carcinoembryonic antigen (CEA) family (1). The CEA family proteins belong to the immunoglobulin (Ig) superfamily and are composed of one Ig variable-like (IgV) and a varying number (0-6) of Ig constant-like (IgC) domains (1,2). CEACAM molecules are membrane-bound either via a transmembrane domain or a glycosylphosphatidyl inositol (GPI) anchor. CEACAM molecules are differentially expressed in epithelial cells or in leucocytes. Over-expression of CEA/CEACAM5 in tumours of epithelial origin is the basis of its wide-spread use as a tumour marker (2). The function of CEACAM family members varies widely: they functio
ImmunogenImmunogen: Immunogen: extracted protein of CEACAM5
Other Names[CD66acde; CGM7], [CEACAM1; CEACAM1; BGP; BGP1; BGPI; BGP; BGP1; BGP-1]
Gene, Accession #Gene ID: 634, NCBI: NP_001020083.1, UniProt: P13688
Catalog #MBS468008
Price$505
Order / More InfoHuman CEACAM1,3,4,5,6 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesZimmermann W (2002). Carcinoembryonic antigen. In Wiley Encyclopedia of Molecular Medicine(T. Creighton, ed.), John Wiley & Sons Inc., New York, USA, pp. 459-462.Hammarstrom S (1999). The carcinoembryonic antigen (CEA) family: structures, suggestedfunctions and expression in normal and malignant tissues. Semin. Cancer Biol. 9, 67-81.Grunert F, AbuHarfeil N, Schwarz K and von Kleist S (1985). Two CEA and three NCAspecies, although distinguishable by monoclonal antibodies, have nearly identical peptidepatterns. Int. J. Cancer 36, 357-362.Grunert F, Stocks SC, Nagel G., Zimmermann W, Thompson JA, Jantscheff P and KromerB. (1996). CD66 family Workshop: Binding of myeloid blind panel antibodies and CD66Subsection antibodies to HeLa transfectants expressing individual CD66 molecules. In LeukocyteTyping VI: White cell Differentiation Antigens (T. Kishimoto et al., eds.), Garland Publishing Inc.,New York and London, pp. 1012-1025.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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