Senp6 - C-terminal region Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Senp6 - C-terminal region |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | cow, dog, horse, human, mouse, porcine, rabbit, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This is a rabbit polyclonal antibody against Senp6. It was validated on Western BlotTarget Description: Senp6 is a protease that deconjugates SUMO1, SUMO2 and SUMO3 from targeted proteins. Senp6 rocesses preferentially poly-SUMO2 and poly-SUMO3 chains, but does not efficiently process SUMO1, SUMO2 and SUMO3 precursors. Senp6 deconjugates SUMO1 from RXRA, leading to transcriptional activation. Senp6 is involved in chromosome alignment and spindle assembly, by regulating the kinetochore CENPH-CENPI-CENPK complex. Senp6 desumoylates PML and CENPI, protecting them from degradation by the ubiquitin ligase RNF4, which targets polysumoylated proteins for proteasomal degradation and desumoylates also RPA1, thus preventing recruitment of RAD |
| Immunogen | n/a |
| Other Names | [sentrin-specific protease 6 isoform 2; Sentrin-specific protease 6; sentrin-specific protease 6; SUMO/sentrin specific peptidase 6; SUMO-1-specific protease 1; Sentrin/SUMO-specific protease SENP6] |
| Gene, Accession # | [SENP6], Gene ID: 215351, NCBI: NP_666115, UniProt: Q6P7W0 |
| Catalog # | MBS3210002 |
| Price | $335 |
| Order / More Info | Senp6 - C-terminal region Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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