CD61/Integrin 3/Platelet Glycoprotein IIIa (Platelet Marker) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD61/Integrin 3/Platelet Glycoprotein IIIa (Platelet Marker)
Clone[ITGB3/2145]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2b, kappa
Formatpurified
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsImmunohistochemistry (IHC) Paraffin
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DescriptionReacts with human integrin beta3 (GPIIIa, vitronectin receptor beta chain). It associates with the IIb-chain (CD41) to form the GpIIb/GpIIIa complex (CD41/CD61).The CD41/CD61 complex appears early in megakaryocyte maturation. The activated CD41/CD61 complex is a receptor for von Willebrand factor, soluble fibrinogen, fibronectin, vitronectin and thrombospondin. It plays a central role in platelet activation and aggregation. The CD51/CD61 is implicated in tumor metastasis and adenoviral infection. The antibody detects platelets in smears of blood and bone marrow, as well as megakaryocytes in frozen sections and cell smears. The antibody is useful for classification of megakaryoblastic leukemia.
ImmunogenImmunogen: Recombinant human ITGB3 protein fragment (aa 385-490) (exact sequence is proprietary)
Other Names[BDPLT2; GP3A; GPIIIa; GT; HPA 1; HPA 4; Integrin beta-3; ITGB3; NAIT; Platelet fibrinogen receptor beta subunit; Platelet glycoprotein IIIa; PTP]
Gene, Accession #[ITGB3], Gene ID: 3690, NCBI: NP_000203.2, UniProt: P05106
Catalog #MBS4381029
Price$190, $340, $340
Order / More InfoCD61/Integrin 3/Platelet Glycoprotein IIIa (Platelet Marker) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesGatter KC, Cordell JL, Turley H, Heryet A, Kieffer N, Anstee DJ, et al. The immunohistological detection of platelets, megakaryocytes and thrombi in routinely processed specimens. Histopathology 1988; 13:257 -67.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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