VCL Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityVCL
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mg
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionSpecificity: Western blot analysis of extracts of various cell lines, using VCL antibody. Immunohistochemistry of paraffin-embedded rat brain using VCL antibody at dilution of 1:200 (400x lens). Vinculin is a cytoskeletal protein that plays an important role in the regulation of focal adhesions and embryonic development (1-4). Three structural vinculin domains include an amino-terminal head, a short, flexible proline-rich region and a carboxy-terminal tail (1). In the inactive state, the head and tail domains of vinculin interact to form a closed confirmation. The open and active form of vinculin translocates to focal adhesions where it is thought to be involved in anchoring F-actin to the membrane and regulation of cell migration (2). Phos
ImmunogenImmunogen: Recombinant protein of human VCL
Other Names[vinculin isoform VCL; Vinculin; vinculin; vinculin; Metavinculin; MV], [VCL; VCL; MV; MVCL; CMD1W; CMH15; HEL114; MV]
Gene, Accession #[VCL], Gene ID: 7414, NCBI: NP_003364.1, UniProt: P18206
Catalog #MBS419802
Price$385
Order / More InfoVCL Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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