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Antigenic Specificity | Insulin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Insulin Polyclonal Antibody detects endogenous levels of Insulin protein. After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. |
Immunogen | Immunogen: Synthesized peptide derived from the internal region of human Insulin |
Other Names | [Rabbit Insulin; Insulin] |
Gene, Accession # | [INS], Gene ID: 3630, NCBI: AAA59172.1, UniProt: P01308 |
Catalog # | MBS9705544 |
Price | $130, $220, $325 |
Order / More Info | Insulin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |