Caspase 7 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCaspase 7
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatepitope affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
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DescriptionThis antibody recognizes ~35 kDa of human Caspase 7. The other species are not tested. Caspase-7 belongs to a member of the cysteine-aspartic acid protease (Caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small. Those dimerize to form the active enzyme. The precursor of this caspase is cleaved by Caspase 3 and 10. It is activated upon cell death stimuli and induces apoptosis. Caspase-7 (CMH-1, Mch3, ICE-LAP3) has been identified as a major contributor to the execution of apoptosis. It is cleaved by many enzymes, including caspases-3, -6,
Immunogenn/a
Other Names[Caspase-7; CASP7; ICE-IAP3; CMH-1; MCH3], [casp7]
Gene, Accession #Gene ID: 100198668, NCBI: NP_001267753.1
Catalog #MBS460133
Price$285
Order / More InfoCaspase 7 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesLippke, J. A et al. Identification and characterization of CPP32/MCH2 homolog 1, a novel cysteine protease similar to CPP32. J. Biol. Chem. 271 (4), 1825-1828 (1996).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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