CD152 (PE) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CD152 (PE) |
| Clone | [WKH203] |
| Host Species | Mouse |
| Reactive Species | rat |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | 5 ul (1 ug)/test |
| Applications | Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The WKH203 monoclonal antibody reacts with rat CD152, also known as the cytotoxic T lymphocyte antigen-4. CTLA-4, a protein with structural similarities to CD28, is expressed on activated T cells and binds the B7 family members, CD80 and CD86, with higher affinity than CD28 does. CTLA-4 and CD28 appear to deliver opposing signals to T cells: while CD28 is a potent costimulator, CTLA-4 restricts the progression of T cells to an activated state by inhibiting IL-2 secretion and cellular proliferation. The cytoplasmic portion of CTLA-4 contains ER retention motifs, resulting in intracellular localization of a large proportion of newly synthesized CTLA-4 in response to TCR signaling. |
| Immunogen | n/a |
| Other Names | [Mouse CD152 (PE); CD152; CD152; CD-152; Ly-56; CD-152; CD152; CD 152; CD 152; CTLA4] |
| Gene, Accession # | [CD152] |
| Catalog # | MBS5309386 |
| Price | $380 |
| Order / More Info | CD152 (PE) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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