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Antigenic Specificity | SNX6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.35 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This SNX6 antibody is generated from rabbits immunized with human SNX6 recombinant protein. SNX6 interacts with members of the transforming growth factor-beta family of receptor serine-threonine kinases. These receptors belong to two classes: type II receptors that bind ligand, and type I receptors that are subsequently recruited to transduce the signal. Of the type II receptors, SNX6 was found to interact strongly with ActRIIB and more moderately with wild type and kinase-defective mutants of TbetaRII. Of the type I receptors, SNX6 was found to interact only with inactivated TbetaRI. SNXs 1-4 also interacted with the transforming growth factor-beta receptor family, showing different receptor preferences. Conversely, SNX6 behaved similarly |
Immunogen | n/a |
Other Names | [Sorting nexin-6; TRAF4-associated factor 2; Sorting nexin-6; N-terminally processed; SNX6] |
Gene, Accession # | [SNX6], Gene ID: 58533, NCBI: NP_067072.3, UniProt: Q9UNH7 |
Catalog # | MBS9200897 |
Price | $165, $370 |
Order / More Info | SNX6 Antibody from MYBIOSOURCE INC. |
Product Specific References | Parks W.T., J. Biol. Chem. 276:19332-19339(2001). |