SHC (Phospho Ser36) Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-SHC (Phospho Ser36) antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | SHC (Phospho Ser36) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.03 mL, 0.1 mL, 0.2 mL |
| Concentration | 1 mg/ml |
| Applications | Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Phospho-Shc (S36) Polyclonal Antibody detects endogenous levels of Shc protein only when phosphorylated at S36. SHC1 (SHC adaptor protein 1) encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2/SOS complex. p66Shc is not involved in Ras activation. Unlike the other two isoforms, p46Shc is targeted to the mitochondrial matrix. Several transcript variants encoding different isoforms have been found for S |
| Immunogen | Immunogen: Synthesized peptide derived from human Shc around the phosphorylation site of S36 |
| Other Names | [Rabbit Shc (phospho Ser36); SHC1; SHC; SHCA; SHC-transforming protein 1; SHC-transforming protein 3; SHC-transforming protein A; Src homology 2 domain-containing-transforming protein C1; SH2 domain protein C1] |
| Gene, Accession # | [SHC], Gene ID: 6464, NCBI: NP_001123512.1, UniProt: P29353 |
| Catalog # | MBS9706814 |
| Price | $130, $220, $325 |
| Order / More Info | SHC (Phospho Ser36) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies