PINK1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPINK1
Clone[S4-15]
Host SpeciesMouse
Reactive Specieshuman, rat, mouse
IsotypeIgG1
Formatunconjugated
Size0.1 mg
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionDetects ~50kDa. Background Info: Detects a 50 kDa protein corresponding to the molecular weight of PINK1 Scientific Background: PINK1 (PTEN induced putative kinase 1) is a mitochondrial serine/threonine kinase which maintains mitochondrial function/integrity, provides protection against mitochondrial dysfunction during cellular stress, potentially by phosphorylating mitochondrial proteins, and is involved in the clearance of damaged mitochondria via selective autophagy (mitophagy). PINK1 is synthesized as a 63 kD protein which undergoes proteolyt processing to generate at least two cleaved forms (55 kD and 42 kD). PINK1 and its substrates have been found in the cytosol as well as in different sub-mitochondrial compartments, and according to
ImmunogenImmunogen: Fusion protein amino acids 112-496 (cytoplasmic C-terminus) of human PINK1. 82% identical to rate and 81% identical to mouse. >30% identity with DMPK.
Other Names[Parkinson disease (autosomal recessive) 6; EC 2.7.11.1; PARK6; serine/threonine-protein kinase PINK1 mitochondrial; PTEN-induced putative kinase protein 1; protein kinase BRPK; BRPK; FLJ27236; PTEN induced putative kinase 1; Phosphatase and Tensin Homolog], [PINK1; PINK1; BRPK; PARK6]
Gene, Accession #Gene ID: 65018, NCBI: NP_115785.1, UniProt: Q9BXM7
Catalog #MBS800448
Price$390
Order / More InfoPINK1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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