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Antigenic Specificity | Phospho-SOX-9 (Ser181) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, chicken |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-SOX-9 (Ser181) antibody detects endogenous levels of SOX-9 only when phosphorylated at Serine 181. Description: SOX9 Plays an important role in the normal skeletal development. May regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes. Defects in SOX9 are the cause of campomelic dysplasia (CMD1).Function: Transcriptional regulator (PubMed:24038782). Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219 (By similarity). Plays a role in chondrocyte differentiation (By similarity). Important for normal skeletal development (PubMed:24038782).Subunit Structure: Interacts (via C-terminus) with ZNF219. |
Immunogen | Immunogen: A synthesized peptide derived from human SOX-9 around the phosphorylation site of Serine 181 Subcellular Location: Nucleus. Predicted Cross Reactivity: Pig, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (92%), Xenopus (92%) |
Other Names | [campomelic dysplasia autosomal sex reversal; CMD 1; CMD1; CMPD 1; CMPD1; SOX 9; Sox9; SOX9_HUMAN; SRA 1; SRA1; SRXX2; SRXY10; SRY (sex determining region Y) box 9 (campomelic dysplasia autosomal; SRY (sex determining region Y) box 9; SRY (sex determining region Y)-box 9; SRY (sex-determining region Y)-box 9 protein; SRY related HMG box gene 9; Transcription factor SOX 9; Transcription factor SOX-9; transcription factor SOX9] |
Gene, Accession # | [SOX-9], Gene ID: 6662, NCBI: NP_000337.1, UniProt: P48436 |
Catalog # | MBS9601099 |
Price | $240, $280 |
Order / More Info | Phospho-SOX-9 (Ser181) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |