IFT57 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityIFT57
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionRequired for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway. Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.
ImmunogenImmunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 170-429 of human IFT57 (NP 060480.1).
Other Names[HIPPI; OFD18; MHS4R2; ESRRBL1]
Gene, Accession #[IFT57], Gene ID: 55081, NCBI: NP_060480.1, UniProt: Q9NWB7
Catalog #MBS8546642
Price$280
Order / More InfoIFT57 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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