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Antigenic Specificity | Human RORA / ROR Alpha |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | reactivity: human, monkey, mouse, rat, bat, bovine, dog, horse, porcine, rabbit (tested or 100% immunogen sequence identity). predicted:chicken, Xenopus, zebrafish (at least 90% immunogen sequence identity) |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mg |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human ROR Alpha. BLAST analysis of the peptide immunogen showed no homology with other human proteins. Retinoid-related orphan receptor alpha (ROR alpha), a NR1 Thyroid Hormone-Like Receptor, has been shown to affect the development of the central nervous system. Deletion of ROR alpha in mice causes severe impairment in the differentiation of cerebellar Purkinje neurons and results in the 'staggerer' phenotype. ROR alpha has been suggested as a potential target in the treatment of chronic inflammatory diseases, including atherosclerosis and rheumatoid arthritis. |
Immunogen | Immunogen Description: Synthetic 20 amino acid peptide from ligand-binding domain of human ROR Alpha. |
Other Names | [RORA / ROR Alpha (Ligand-binding Domain) IHC-plus; RORA; Nuclear receptor ROR-alpha; Nuclear receptor RZR-alpha; Roralpha; Transcription factor RZR-alpha; RAR-related orphan receptor A; ROR-alpha; ROR3; RZRA; NR1F1; ROR Alpha; RZR-ALPHA; Human RORA; ROR Alpha], [RORA; RORA; ROR1; ROR2; ROR3; RZRA; NR1F1; RZR-ALPHA; NR1F1; RZRA] |
Gene, Accession # | [RORA], Gene ID: 6095, NCBI: NP_002934.1, UniProt: P35398 |
Catalog # | MBS243643 |
Price | $530 |
Order / More Info | Human RORA / ROR Alpha Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |