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Antigenic Specificity | TRADD |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, monkey |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: TRADD Polyclonal Antibody detects endogenous levels of TRADD protein. Tumor necrosis factor receptor type 1-associated DEATH domain protein encoded by TRADD is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. Tumor necrosis factor receptor type 1-associated DEATH domain protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. |
Immunogen | Immunogen: Synthesized peptide derived from the C-terminal region of human TRADD at AA range: 220-300 |
Other Names | [Rabbit TRADD; TRADD; Tumor necrosis factor receptor type 1-associated DEATH domain protein; TNFR1-associated DEATH domain protein; TNFRSF1A-associated via death domain] |
Gene, Accession # | [TRADD], Gene ID: 8717, NCBI: NP_003780.1, UniProt: Q15628 |
Catalog # | MBS9703300 |
Price | $130, $220, $325 |
Order / More Info | TRADD Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |