PEDF Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-PEDF antibody, protein, ELISA kits.
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| Antigenic Specificity | PEDF |
| Clone | polyclonal |
| Host Species | Goat |
| Reactive Species | human |
| Isotype | n/a |
| Format | biotin conjugate |
| Size | 0.05 mg |
| Concentration | 1.0 mg/mL after reconstitution. |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: alpha-PEDF Antibody reacts specifically with PEDF by Western Blotting. Recommended dilution range for Westernanalysis:1:500 -1:2,500. Recommended starting dilution: 1:1,000. Background: Pigment epithelium-derived factor (PEDF) is a protein that acts in neuronal differentiation and survival in cells derived from the retina and CNS. PEDF inhibits angiogenesis and its expression is down-regulated over the replicative lifespan of mammals. This interesting factor is secreted by retinal pigment epithelial cells into the interphotoreceptor matrix, where it acts on photoreceptor cells. PEDF receptors have been localized to photoreceptors, those cells that are protected from light-induced damage and apoptosis. PEDF promotes neuronal sur |
| Immunogen | Immunogen: human recombinant PEDF. Source Notes: Biotinylated alpha-PEDF Antibody is an affinity purified goat polyclonal antibody raised against purified human PEDF protein. |
| Other Names | [GOAT AFFINITY PUR.], [SERPINF1; OI6; OI12; PEDF; EPC-1; PIG35] |
| Gene, Accession # | [alpha-PEDF], Gene ID: 5176, NCBI: NP_002606.3 |
| Catalog # | MBS412005 |
| Price | $355 |
| Order / More Info | PEDF Antibody from MYBIOSOURCE INC. |
| Product Specific References | Becerra SP. (1997) Structure-function studies on PEDF. A non-inhibitory serpin with neurotrophic activity. Adv Exp Med Biol, 425, 223-237.Cao, W, Tombran-Tink, J, Elias, R, Sezate,S, Mrazed, D, McGinnis, JF. (2001) In vivo protection of photoreceptors from light damage by pigment epithelium-derived factor. Invest Ophthalmol Vis Sci, 42, 1646-1652.Cayouette M, Smith SB, Becerra SP, Gravel C. (1999) Pigment epithelium-derived factor delays the death of photoreceptors in mouse models of inherited retinal degenerations. Neurobiol Dis, Dec;6(6), 523-532.Dawson DW, Volpert OV, Gillis P, Crawford SE, Xu H, Benedict W, Bouck NP. (1999) Pigment epithelium-derived factor: a potent inhibitor of angiogenesis. Science, 285(5425), 245-248.Houenou, LJ, D'Costa, AP, Li, L, Turgeon, VL, Enyadike, C, Alberdi, E, and Becerra, SP. (1999) Pigment epithelium-derived factor promotes the survival and differentiation of developing spinal motor neurons. J. Comp Neurol, 412, 506-514Jablonski, MM, Tombran-Tink, J, Mrazed, DA, and Iannaccone, A. (2000) Pigment epithelium-derived factor supports normal development of photoreceptor neurons and opsin expression after retinal pigment epithelium removal. J. Neurosci, 20, 7149-7157.Mori, K, Gehlbach, P, Ando, A, McVey, D, Wei, L, and Campochiaro, PA. (2002) Regression of ocular neovascularization in response to increased expression of pigment epithelium-derived factor. Invest Ophthalmol Vis Sci, 43, 2428-2434.Stellmach, V, Crawford, SE, Zhou, W, and Bouck, N. (2001) Prevention of ischemia-induced retinopathy by the natural ocular antiangiogenic agent pigment epithelium-derived factor. Proc Natl Acad Sci USA, 98, 2593-2597. |
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