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Antigenic Specificity | CHOP; GADD153 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CHOP, also known as GADD153 or DDIT3, is a highly conserved gene in both the structural and regulatory regions to hamster gene.Imposed by unfolded and malfolded proteins, CHOP is significantly induced by ER stress, deficiency of CHOP prevents cell from ER stress. CHOP is considered a proapoptotic marker of ER stress dependent cell death. CHOP acts as a dominant-negative inhibitor of the transcription factor C/EBP and LAP by forming a heterodimer. It may play an important role in the malignant transformation of nevus to melanoma. The observed molecular weight of CHOP is about 30 kDa. |
Immunogen | Immunogen: Fusion protein of CHOP; GADD153 |
Other Names | [CCEBPZ, CHOP, CHOP 10, DDIT 3, DDIT3, GADD153] |
Gene, Accession # | [CHOP], NCBI: BC003637, UniProt: P35638 |
Catalog # | MBS2524492 |
Price | $195, $270, $435 |
Order / More Info | CHOP; GADD153 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |