CHOP; GADD153 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCHOP; GADD153
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatantigen affinity purified
Size0.06 mL, 0.12 mL, 0.2 mL
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
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DescriptionCHOP, also known as GADD153 or DDIT3, is a highly conserved gene in both the structural and regulatory regions to hamster gene.Imposed by unfolded and malfolded proteins, CHOP is significantly induced by ER stress, deficiency of CHOP prevents cell from ER stress. CHOP is considered a proapoptotic marker of ER stress dependent cell death. CHOP acts as a dominant-negative inhibitor of the transcription factor C/EBP and LAP by forming a heterodimer. It may play an important role in the malignant transformation of nevus to melanoma. The observed molecular weight of CHOP is about 30 kDa.
ImmunogenImmunogen: Fusion protein of CHOP; GADD153
Other Names[CCEBPZ, CHOP, CHOP 10, DDIT 3, DDIT3, GADD153]
Gene, Accession #[CHOP], NCBI: BC003637, UniProt: P35638
Catalog #MBS2524492
Price$195, $270, $435
Order / More InfoCHOP; GADD153 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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