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Antigenic Specificity | KDM5C |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | n/a |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody detects endogenous levels of KDM5C and does not corss-react with related proteins. UniPort Summary Function: Histone demethylase that specifically demethylates ?Lys-4? of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 ?Lys-9?, H3 ?Lys-27?, H3 ?Lys-36?, H3 ?Lys-79? or H4 ?Lys-20?. Demethylates trimethylated and dimethylated but not monomethylated H3 ?Lys-4?. Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements. Entrez Summary: This gene is a member of the SMCY homolog family and encodes a protein with one ARID domain, one JmjC domain, one JmjN domain and two PHD-type zinc fingers. The DNA-bind |
Immunogen | Immunogen: Purified recombinant human KDM5C (C-terminus) protein fragments expressed in E Coli. Cellular Localization: Nucleus |
Other Names | [MRXJ; SMCX; MRXSJ; XE169; MRXSCJ; JARID1C; DXS1272E], [MRXJ; SMCX; MRXSJ; XE169; MRXSCJ; JARID1C; DXS1272E] |
Gene, Accession # | [KDM5C], UniProt: P412298 |
Catalog # | MBS857783 |
Price | $300 |
Order / More Info | KDM5C Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |