DRD3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityDRD3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: DRD3 antibody detects endogenous levels of total DRD3. Function: Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Promotes cell proliferation.Subunit Structure: Interacts with CLIC6 (By similarity). Interacts with GRK4 (PubMed:19520868). Interacts with PALM (PubMed:16386234). Interacts with FLNA (via filamin repeat 21); increases PKA-mediated phosphorylation of FLNA (PubMed:26460884).Post-translational Modifications: Phosphorylated by GRK4 (GRK4-alpha and GRK4-gamma). Palmitoylated.Similarity: Belongs to the G-protein coupled receptor 1 family.
ImmunogenImmunogen: A synthesized peptide derived from human DRD3 Subcellular Location: Cell Membrane. Both membrane-bound and scattered in the cytoplasm during basal conditions. Receptor stimulation results in the rapid internalization and sequestration of the receptors at the perinuclear area (5 and 15 minutes), followed by the dispersal of the receptors to the membrane (30 minutes). DRD3 and GRK4 co-localize in lipid rafts of renal proximal tubule cells. Tissue Specificity: Brain. Predicted Cross Reac
Other Names[3dopamine receptor; D; D(3) dopamine receptor; Dopamine D3 receptor; Dopamine receptor D3; DRD3; DRD3_HUMAN; ETM1; FET1]
Gene, Accession #[DRD3], Gene ID: 1814, NCBI: NP_000787.2, UniProt: P35462
Catalog #MBS9603070
Price$240, $280
Order / More InfoDRD3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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