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Antigenic Specificity | DRD3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: DRD3 antibody detects endogenous levels of total DRD3. Function: Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Promotes cell proliferation.Subunit Structure: Interacts with CLIC6 (By similarity). Interacts with GRK4 (PubMed:19520868). Interacts with PALM (PubMed:16386234). Interacts with FLNA (via filamin repeat 21); increases PKA-mediated phosphorylation of FLNA (PubMed:26460884).Post-translational Modifications: Phosphorylated by GRK4 (GRK4-alpha and GRK4-gamma). Palmitoylated.Similarity: Belongs to the G-protein coupled receptor 1 family. |
Immunogen | Immunogen: A synthesized peptide derived from human DRD3 Subcellular Location: Cell Membrane. Both membrane-bound and scattered in the cytoplasm during basal conditions. Receptor stimulation results in the rapid internalization and sequestration of the receptors at the perinuclear area (5 and 15 minutes), followed by the dispersal of the receptors to the membrane (30 minutes). DRD3 and GRK4 co-localize in lipid rafts of renal proximal tubule cells. Tissue Specificity: Brain. Predicted Cross Reac |
Other Names | [3dopamine receptor; D; D(3) dopamine receptor; Dopamine D3 receptor; Dopamine receptor D3; DRD3; DRD3_HUMAN; ETM1; FET1] |
Gene, Accession # | [DRD3], Gene ID: 1814, NCBI: NP_000787.2, UniProt: P35462 |
Catalog # | MBS9603070 |
Price | $240, $280 |
Order / More Info | DRD3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |