Edit |   |
---|---|
Antigenic Specificity | HDAC2 |
Clone | [2D9-F6-G7] |
Host Species | Mouse |
Reactive Species | human, mouse, rat, monkey |
Isotype | IgG2b |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody detects endogenous levels of HDAC2 and does not cross-react with related proteins. Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Forms transcriptional repressor complexes by associating with MAD, SIN3, YY1 and N-COR. Interacts in the late S-phase of DNA-replication with DNMT1 in the other transcriptional repressor complex composed of DNMT1, DMAP1, PCNA, CAF1. Deacetylates TSHZ3 and regulates its transcriptional rep |
Immunogen | Immunogen: Purified recombinant human HDAC2 protein fragments expressed in E.coli. |
Other Names | [D10Wsu179e; HD 2; HD2; HDAC 2; Hdac2; HDAC2_HUMAN; Histone deacetylase 2 (HD2); Histone deacetylase 2; OTTHUMP00000017046; OTTHUMP00000227077; OTTHUMP00000227078; RPD3; transcriptional regulator homolog RPD3; YAF1; YY1 associated factor 1; YY1 transcription factor binding protein; Yy1bp], [HD2; RPD3; YAF1; HDAC2] |
Gene, Accession # | [HDAC2], Gene ID: 3066, NCBI: NP_001518.3, UniProt: Q92769 |
Catalog # | MBS477377 |
Price | $335 |
Order / More Info | HDAC2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |