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Antigenic Specificity | ADAM17 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Disintegrin and metalloproteinase domain-containing protein 17(ADAM17) detection. Tested with WB in Human, Mouse, Rat. Background: ADAM17(ADAM metallopeptidase domain 17), also called TACE (tumor necrosis factor-alpha-converting enzyme), is a 70-kDa enzyme that belongs to the ADAM protein family of disintegrins and metalloproteases. Expression studies showed that the encoded protein cleaves precursor tumor necrosis factor-alpha to its mature form. Northern blot analysis revealed that the gene was expressed as a 5-kb mRNA in all tissues examined. ADAM17 is understood to be involved in the processing of tumor necrosis factor alpha(TNF-alpha) at the surface of the cell, and from within theintrace |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human ADAM17 (806-824aa AASFKLQRQNRVDSKETEC), different from the related rat and mouse sequences by one amino acid. |
Other Names | [Disintegrin and metalloproteinase domain-containing protein 17(ADAM 17); ADAM metallopeptidase domain 17; A disintegrin and metalloproteinase domain 17(tumor necrosis factor, alpha, converting enzyme); A disintegrin and metalloproteinase domain 17; ADA17_HUMAN; ADAM 17; ADAM metallopeptidase domain 17; ADAM17; ADAM17 protein; CD 156b; CD156b; CD156b antigen; CSVP; Disintegrin and metalloproteinase domain-containing protein 17; MGC71942; Snake venom like protease; Snake venom-like protease; TACE; TNF alpha convertase; TNF alpha converting enzyme; TNF-alpha convertase; TNF-alpha-converting enzyme; Tumor Necrosis Factor Alpha Converting Enzyme], [ADAM17; ADAM17; CSVP; TACE; NISBD; ADAM18; CD156B; CSVP; TACE; ADAM 17] |
Gene, Accession # | [ADAM17], Gene ID: 6868, NCBI: P78536.1, UniProt: P78536 |
Catalog # | MBS176185 |
Price | $280 |
Order / More Info | ADAM17 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |