ADAM17 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityADAM17
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionDescription: Rabbit IgG polyclonal antibody for Disintegrin and metalloproteinase domain-containing protein 17(ADAM17) detection. Tested with WB in Human, Mouse, Rat. Background: ADAM17(ADAM metallopeptidase domain 17), also called TACE (tumor necrosis factor-alpha-converting enzyme), is a 70-kDa enzyme that belongs to the ADAM protein family of disintegrins and metalloproteases. Expression studies showed that the encoded protein cleaves precursor tumor necrosis factor-alpha to its mature form. Northern blot analysis revealed that the gene was expressed as a 5-kb mRNA in all tissues examined. ADAM17 is understood to be involved in the processing of tumor necrosis factor alpha(TNF-alpha) at the surface of the cell, and from within theintrace
ImmunogenImmunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human ADAM17 (806-824aa AASFKLQRQNRVDSKETEC), different from the related rat and mouse sequences by one amino acid.
Other Names[Disintegrin and metalloproteinase domain-containing protein 17(ADAM 17); ADAM metallopeptidase domain 17; A disintegrin and metalloproteinase domain 17(tumor necrosis factor, alpha, converting enzyme); A disintegrin and metalloproteinase domain 17; ADA17_HUMAN; ADAM 17; ADAM metallopeptidase domain 17; ADAM17; ADAM17 protein; CD 156b; CD156b; CD156b antigen; CSVP; Disintegrin and metalloproteinase domain-containing protein 17; MGC71942; Snake venom like protease; Snake venom-like protease; TACE; TNF alpha convertase; TNF alpha converting enzyme; TNF-alpha convertase; TNF-alpha-converting enzyme; Tumor Necrosis Factor Alpha Converting Enzyme], [ADAM17; ADAM17; CSVP; TACE; NISBD; ADAM18; CD156B; CSVP; TACE; ADAM 17]
Gene, Accession #[ADAM17], Gene ID: 6868, NCBI: P78536.1, UniProt: P78536
Catalog #MBS176185
Price$280
Order / More InfoADAM17 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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