GSK-3alpha Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityGSK-3alpha
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.03 mg, 0.1 mg
Concentration0.5 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionPolyclonal Antibody to detect GSK-3alpha in human samples. Background: Glycogen synthase kinase 3-alpha is a multifunctional protein serine kinase. GSK-3 phosphorylates and inactivates glycogen synthase. It has also been implicated in the regulation of cell fate in Dictyostelium and is a component of the Wnt signaling pathway required for Drosophila, Xenopus, and mammalian development. GSK-3 has been shown to regulate Cyclin D1 proteolysis and subcellular localization. GSK-3alpha (GSK-3alpha) regulates the production of amyloid-beta peptides, a major component of the plaques that accumulate with progression of Alzheimer's disease, by phosphorylating Tau proteins. This presents the possibility that defects in GSK-3 signaling can contribute t
ImmunogenImmunogen: Human recombinant GSK-3alpha. Positive Control: Western Blot: 3T3 cell lysate
Other Names[Serine/threonine-protein kinase GSK3A; GSK-3alpha; Glycogen synthase kinase-3; GSK-3 alpha], [GSK3A; GSK3A; GSK-3 alpha]
Gene, Accession #Gene ID: 2931, NCBI: NP_063937.2, UniProt: P49840
Catalog #MBS840780
Price$150, $305
Order / More InfoGSK-3alpha Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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