Akt (Thr-34), phospho-specific Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Akt (Thr-34), phospho-specific |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, rat, rabbit |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | ELISA, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects a 60 kDa* protein corresponding to the apparent molecular mass of phoshorylated Akt on SDS-PAGE immunoblots of A431 + calyculin A cell lysate. Similar results were seen in calyculin A treated human aortic endothelial and HeLa cells, rabbit spleen fibroblasts, and rat pituitary cells. Akt, also known as Protein Kinase B (PKB) and Rac (Related to the A and C kinases), is a 60kDa serine/threonine kinase critical for controlling diverse cellular functions, including glucose metabolism, gene transcription, cell proliferation, and apoptosis. Akt phosphorylates a number of physiological substrates including MBP, glycogen synthetase, PKA RII subunit, and histone H1. Akt is activated in response to insulin and growth factors in |
| Immunogen | Immunogen: Phospho-Akt (Thr-34) synthetic peptide (coupled to KLH) corresponding to amino acid residues around threonine 34 of human Akt. This sequence is highly conserved in rat and mouse Akt. |
| Other Names | n/a |
| Gene, Accession # | n/a |
| Catalog # | MBS472002 |
| Price | $385 |
| Order / More Info | Akt (Thr-34), phospho-specific Antibody from MYBIOSOURCE INC. |
| Product Specific References | • Jones, P.F. et al. (1991) Proc. Natl. Acad. Sci. USA 88:4171-4175.• Marte, B. & Downward. J. (1997) TIBS. 22:355-358.• Powell, D.J. et al. (2003) Mol. Cell Biol. 23:7794-7808. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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