Catenin-b (pS675) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCatenin-b (pS675)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatepitope affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
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DescriptionBeta-catenin, a cytosolic, 88 kDa, 781 amino acid protein, belongs to the beta-catenin family. The N-terminus domain, contains the binding site and the phosphorylation sites. Beta-Catenin serves as a link between cytoskeleton actin and transmembrane cadherin (s). It is believed to contribute to tight cell-to-cell adhesion. It can enter the nucleus and interact with the TCF/LEF family of transcription factors, initiating gene expression. Normally, beta-catenin transcriptional activity is suppressed by a Ser/Thr kinase termed GSK3beta and/or Casein Kinase I (CK1). Kinases are constitutively active and phosphorylates beta-catenin at multiple sites, including S33 and S37, Y96, Y228, Y280, S675, etc. Phosphorylation of beta-catenin targets the m
Immunogenn/a
Other Namesn/a
Gene, Accession #Gene ID: 1499
Catalog #MBS460295
Price$285
Order / More InfoCatenin-b (pS675) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesPark, C.S. et al. (2004) J. Biol. Chem. 279:19592.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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