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Antigenic Specificity | Human DNA repair protein RAD51 homolog 4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. Bind to single-stranded DNA (ssDNA) and has DNA-dependent ATPase activity. Part of the Rad21 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, BCDX2 acts downstream of BRCA2 recruitment and upstream of RAD51 recruitment. BCDX2 binds predominantly to the intersection of the four duplex arms of the Holliday junction and to junction of replication forks. The BCDX2 complex was originally reported to bind single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. Involved in telomere maintenance. The BCDX |
Immunogen | Immunogen: Recombinant human DNA repair protein RAD51 homolog 4 protein(1-328aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-33089 / sc-33090 |
Other Names | [R51H3; RAD51 homolog D; RAD51-like protein 3; TRAD; RAD51D; RAD51L3], [RAD51D; RAD51D; TRAD; R51H3; BROVCA4; RAD51L3; RAD51L3] |
Gene, Accession # | [RAD51D], Gene ID: 5892, NCBI: NP_001136043.1, UniProt: O75771 |
Catalog # | MBS1492373 |
Price | $120, $160 |
Order / More Info | Human DNA repair protein RAD51 homolog 4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |