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Antigenic Specificity | RAB21 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: RAB21 antibody detects endogenous levels of total RAB21. Function: Regulates integrin internalization and recycling, but does not influence the traffic of endosomally translocated receptors in general. As a result, may regulate cell adhesion and migration (By similarity). During the mitosis of adherent cells, controls the endosomal trafficking of integrins which is required for the successful completion of cytokinesis. Involved in neurite growth (By similarity).Subunit Structure: Interacts with the cytoplasmic tail of integrins ITGA1, ITGA2, ITGA5, ITGA6, ITGA11 and ITGB1 (By similarity). Interacts with RABGEF1 (via VPS9 domain). Interacts with ANKRD27 (PubMed:16525121, PubMed:18477474).Similarity: Belongs to the small |
Immunogen | Immunogen: A synthesized peptide derived from human RAB21 Subcellular Location: Endoplasmic Reticulum Membrane. Golgi Apparatus Membrane. Early Endosome Membrane. Cytoplasmic Vesicle Membrane. Cleavage Furrow. In nonpolarized epithelial Caco-2 cells, found in the endoplasmic reticulum; in polarized cells, observed in vesicles in the apical cytoplasm. During mitosis, in mid-telophase, localized in the ingressing cleavage furrow. In late telophase, detected at the opposite poles of the daughter ce |
Other Names | [KIAA0118; RAB 21; RAB21; RAB21, member RAS oncogene family; RAB21_HUMAN; Ras-related protein Rab-21] |
Gene, Accession # | [RAB21], Gene ID: 23011, NCBI: NP_055814.1, UniProt: Q9UL25 |
Catalog # | MBS9610135 |
Price | $240, $280 |
Order / More Info | RAB21 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |