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Antigenic Specificity | VPS39 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mousepredicted: porcine, bovine, horse, sheep, rabbit, dog, chicken |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: VPS39 Antibody detects endogenous levels of VPS39. Description: Regulator of TGF-beta/activin signaling, inhibiting SMAD3- and activating SMAD2-dependent transcription. Acts by interfering with SMAD3/SMAD4 complex formation, this would lead to inhibition of SMAD3-dependent transcription and relieve SMAD3 inhibition of SMAD2-dependent promoters, thus increasing SMAD2-dependent transcription. Does not affect TGF-beta-induced SMAD2 or SMAD3 phosphorylation, nor SMAD2/SMAD4 complex formation.Subunit Structure: Homooligomer (PubMed:11448994). Interacts with TGFBR2 and, less efficiently, with TGFBR1; interaction with TGFBR2 is independent of the receptor kinase activity and of the presence of TGF-beta. Also interacts with ACV |
Immunogen | Immunogen: A synthesized peptide derived from human VPS39. Tissue Specificity: Widely expressed, with highest levels in heart, skeletal muscle, kidney, pancreas, brain, placenta and spleen. |
Other Names | [A230065P22Rik; AW743070; FLJ21681; FLJ46546; hVam6p; KIAA0770; RP23-348L16.12; TLP; TRAP1 like protein; Vacuolar protein sorting 39; Vacuolar protein sorting 39 homolog; VAM6; Vam6/Vps39 like; Vam6/Vps39 like protein; Vam6/Vps39-like protein; VPS 39; Vps39; VPS39_HUMAN] |
Gene, Accession # | [VPS39], Gene ID: 23339, NCBI: AAQ05978, UniProt: Q96JC1 |
Catalog # | MBS9611545 |
Price | $240, $280 |
Order / More Info | VPS39 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |