Bcl-xL (pSer62) Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | Bcl-xL (pSer62) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse (expected from sequence), rat (expected from sequence) |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.05 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti Bcl-xL (pSer62) antibody recognizes Bcl-xL, also known as Bcl-2-like protein 1 (Bcl-2-L-1) and apoptosis regulator Bcl-X, when phosphorylated at serine 62. Bcl-xL is a Bcl-2 family member that has an anti-apoptotic function in the apoptosis signaling cascade. Bcl-xL inhibits apoptosis by preventing the release of mitochondrial cytochrome c and the subsequent activation of caspases 3 and 9. Mitotic arrest induces complete phosphorylation of Bcl-xL at serine 62 by cyclin dependent kinase 1 (CDK1), inactivating the anti-apoptotic function of Bcl-xL (Terrano et al. 2010). |
| Immunogen | Immunogen: Phospho specific-peptide corresponding to residues surrounding serine 62 of human Bcl-xL |
| Other Names | [Bcl-xL (pSer62)], [BCL2L1; BCL2L1; BCLX; BCL2L; Bcl-X; PPP1R52; BCL-XL/S; BCL2L; BCLX; Bcl2-L-1] |
| Gene, Accession # | [BCL2L1], Gene ID: 598, NCBI: Q07817.1, UniProt: Q07817 |
| Catalog # | MBS225197 |
| Price | $375 |
| Order / More Info | Bcl-xL (pSer62) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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