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Antigenic Specificity | JARID2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | biotin conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Regulator of histone methyltransferase complexes that plays an essential role in embryonic development, including heart and liver development, neural tube fusion process and hematopoiesis. Acts by modulating histone methyltransferase activity and promoting the recruitment of histone methyltransferase complexes to their target genes. Binds DNA and mediates the recruitment of the PRC2 complex to target genes in embryonic stem cells. Does not have histone demethylase activity but regulates activity of various histone methyltransferase complexes. In embryonic stem cells, it associates with the PRC2 complex and inhibits trimethylation of 'Lys-27' of histone H3 (H3K27me3) by the PRC2 complex, thereby playing a key role in differentiation of embry |
Immunogen | Immunogen: Recombinant human Protein Jumonji protein |
Other Names | [Protein Jumonji; Jumonji/ARID domain-containing protein 2; JARID2; JMJ] |
Gene, Accession # | [JARID2], Gene ID: 3720, NCBI: NP_001253969.1, UniProt: Q92833 |
Catalog # | MBS7043965 |
Price | $160, $235 |
Order / More Info | JARID2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |