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Antigenic Specificity | ORC3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ORC3 antibody detects endogenous levels of total ORC3. Function: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3.Subunit Structure: Component of ORC, a complex composed of at least 6 subunits: ORC1, ORC2, ORC3, ORC4, ORC5 and ORC6. ORC is regulated in a cell-cycle dependent manner. It is sequentially assembled at the exit from anaphase of mitosis and disassembled as cells enter S phase.Similarity |
Immunogen | Immunogen: A synthesized peptide derived from human ORC3 Subcellular Location: Nucleus. |
Other Names | [Homolog of Latheo; homolog of latheo, Drosophila; LAT; LATHEO; LATHEO, drosophila, homolog of; orc3; ORC3_HUMAN; ORC3L; Origin recognition complex subunit 3; Origin recognition complex subunit 3 honolog; Origin Recognition Complex Subunit 3 Isoform 1; Origin recognition complex subunit 3 like; Origin recognition complex subunit Latheo; Origin Recognition Complex, subunit 3, S. cerevisiae, homolog of; Origin recognition complex, subunit 3-like (S. cerevisiae); Origin recognition complex, subunit 3-like (yeast)] |
Gene, Accession # | [ORC3], Gene ID: 23595, NCBI: NP_001184188.1, UniProt: Q9UBD5 |
Catalog # | MBS9602985 |
Price | $240, $280 |
Order / More Info | ORC3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |