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Antigenic Specificity | SMAD5 |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SMAD5 is a member of the Mothers Against Dpp (MAD)-related family of proteins. It is a receptor-regulated SMAD (R-SMAD), and acts as an intracellular signal transducer for the transforming growth factor beta superfamily. SMAD5 is activated through serine phosphorylation by BMP (bone morphogenetic proteins) type 1 receptor kinase. It is cytoplasmic in the absence of its ligand and migrates into the nucleus upon phosphorylation and complex formation with SMAD4. Here the SMAD5/SMAD4 complex stimulates the transcription of target genes. |
Immunogen | Immunogen: Recombinant fragment of human SMAD5 (C-terminus). Preservative: 0.02% Sodium Azide and 50% glycerol. 1% BSA, PBS, pH7.4. Cellular Localization: Nucleus |
Other Names | [Mouse IgG to SMAD5], [SMAD5; SMAD5; DWFC; JV5-1; MADH5; MADH5; MAD homolog 5; Mothers against DPP homolog 5; SMAD 5; Smad5; hSmad5] |
Gene, Accession # | [SMAD5], Gene ID: 4090, NCBI: NP_001001420.1, UniProt: Q99717 |
Catalog # | MBS857801 |
Price | $280 |
Order / More Info | SMAD5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |