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Antigenic Specificity | hCD98 |
Clone | [ABM5A27] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | Protein G purified |
Size | 0.025 mg, 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD98 was originally identified as a cell surface antigen associated with lymphocyte activation defined by 4F2 mAb; it is expressed in proliferating normal tissues and in almost all tumor cells. CD98 heterodimer consists of a type II single-pass transmembrane heavy chain (CD98hc, also known as 4F2 antigen heavy chain or FRP-1; encoded by the genes SLC3A2 and Slc3a2 for human and mouse, respectively) of ~80-85 kDa that is disulfide-linked with a multi-pass light chain of ~40 kDa. CD98 hc (heavy chain) is a type II transmembrane glycoprotein that is disulfide-linked to a non-glycosylated light chain of a member of the permease family. It has been reported that CD98 was functionally involved in lymphocyte activation, cell proliferation, and mal |
Immunogen | Antigen: hCD98. Immunogen Information: A partial length recombinant protein (a.a 162-371) of hCD98 was used as the immunogen for this antibody. Conjugation: Unconjugated |
Other Names | [4F2 cell-surface antigen heavy chain; 4F2 heavy chain antigen; Lymphocyte activation antigen 4F2 large subunit; Solute carrier family 3 member 2], [SLC3A2] |
Gene, Accession # | [hCD98], Gene ID: 6520, NCBI: NP_001012680.1, UniProt: P08195 |
Catalog # | MBS669005 |
Price | $145, $290 |
Order / More Info | hCD98 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |