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Antigenic Specificity | p95/NBS1 (Phospho-Ser343) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of p95/NBS1 only when phosphorylated at serine 343. Mutations in p95/NBS1 gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of serine 343 (S-L-S(p)-Q-G) derived from Human p95/NBS1. |
Other Names | [NBN] |
Gene, Accession # | [p95/NBS1], Gene ID: 4683, NCBI: NP_001019859.1, UniProt: O60934 |
Catalog # | MBS9413224 |
Price | $200, $255 |
Order / More Info | p95/NBS1 (Phospho-Ser343) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |