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Antigenic Specificity | ASC |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunoblot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Anti-ASC [Rabbit antibody to peptide corresponding to aa 182-195 of human ASC.]. This antibody recognizes human ASC (25 kD). Apoptosis is regulated by death domain (DD)- and/or caspase recruitment domain (CARD)-containing molecules and a caspase family of proteases. CARD containing cell death regulators include RAIDD, RICK, BCL10, Apaf-1, ARC, caspase-2, and caspase-9. A novel CARDcontaining protein was recently identified and designated ASC (or TMS1). ASC induces apoptosis by activating caspase-9 and inhibits survival of human breast cancer cells. ASC is widely expressed in human and mouse tissues. |
Immunogen | Antigen: Peptide corresponding to aa 182- 195 of human ASC. |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS194028 |
Price | $415 |
Order / More Info | ASC Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |