Hsp90 alpha Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHsp90 alpha
Clone[M10E3R]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2a
FormatProtein A purified
Size0.1 mg
Concentration1 mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionDetects 90 kDa. Does not detect HSP90 beta. HSP90 is an abundantly and ubiquitously expressed heat shock protein. It is understood to exist in two principal forms alpha and beta, which share 85% sequence amino acid homology. The two isoforms of HSP90, are expressed in the cytosolic compartment (1). Despite the similarities, HSP90alpha exists predominantly as a homodimer while HSP90beta exists mainly as a monomer (2). From a functional perspective, HSP90 participates in the folding, assembly, maturation, and stabilization of specific proteins as an integral component of a chaperone complex (3-6). Furthermore, HSP90 is highly conserved between species; having 60% and 78% amino acid similarity between mammalian and the corresponding yeast and
ImmunogenImmunogen: Purified HSP90. Immunogen Species: Human. Cellular Localization: Cytoplasm; Melanosome. Conjugate: Unconjugated. Storage Buffer: PBS pH 7.4, 50% glycerol, 0.09% Sodium Azide
Other Names[Mouse Human Hsp90 alpha Recombinant IgG2a; Hsp90 alpha; HSP86; HSP89A; HSP90A; HSP90AA1; HSP90Alpha; HSPC1; HSPCA; HSPCAL3], [HSP90AA1; HSP90AA1; EL52; HSPN; LAP2; HSP86; HSPC1; HSPCA; Hsp89; Hsp90; LAP-2; HSP89A; HSP90A; HSP90N; Hsp103; HSPCAL1; HSPCAL4; HEL-S-65p; HSP90A; HSPC1; HSPCA; HSP 86; HSP86; LAP-2; LPS-associated protein 2]
Gene, Accession #[Hsp90 alpha], Gene ID: 3320, NCBI: NP_001017963.2, UniProt: P07900
Catalog #MBS809348
Price$410
Order / More InfoHsp90 alpha Antibody from MYBIOSOURCE INC.
Product Specific References1. Nemoto, T. et al. (1997) J.Biol Chem. 272: 26179-26187. 2. Minami, Y, et al. (1991), J.Biol Chem. 266: 10099-10103. 3. Arlander SJH, et al. (2003) J Biol Chem. 278: 52572-52577. 4. Pearl H, et al. (2001) Adv Protein Chem. 59: 157-186. 5. Neckers L, et al. (2002) Trends Mol Med. 8: S55-S61. 6. Pratt W, Toft D. (2003) Exp Biol Med. 228: 111-133. 7. Pratt W, Toft D. (1997) Endocr Rev. 18: 306-360. 8. Pratt WB. (1998) Proc Soc Exptl Biol Med. 217: 420-434. 9. Whitesell L, et al. (1994) Proc Natl Acad Sci USA. 91: 8324-8328. 10. Nemoto, T. (1997) Biochem and Mol. Bio Intl. 42 (5): 881-889.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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