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Antigenic Specificity | Human-SHB (Y268) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 250-290 amino acids from human. Adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. May play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. May also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic- FGF and NGF-induced signaling cascades. May also regulate IRS1 and IRS2 signaling in insulin-producing cells. |
Immunogen | n/a |
Other Names | [SH2 domain-containing adapter protein B; SHB] |
Gene, Accession # | [SHB], Gene ID: 6461, NCBI: NP_003019.2, UniProt: Q15464 |
Catalog # | MBS9205724 |
Price | $165, $370 |
Order / More Info | Human-SHB (Y268) Antibody from MYBIOSOURCE INC. |
Product Specific References | Welsh M.,et al.Oncogene 9:19-27(1994). Humphray S.J.,et al.Nature 429:369-374(2004). Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. Karlsson T.,et al.Oncogene 10:1475-1483(1995). Karlsson T.,et al.Oncogene 13:955-961(1996). |